It depends entirely on your specific engine block, exhaust header clearance, and how you plan to route the wires. Take a look at your current wire setup and where the exhaust pipes sit to determine which angle will give you the most clearance.
45-degree / 135-degree boots offer a middle ground, perfect for sneaking around bulky aftermarket headers.
90-degree boots are best when you need the wire to immediately turn away from the spark plug to hug the engine block.
Straight boots are ideal for engines where the plug sits deep in the cylinder head or has a clear, unobstructed path outward.